“Use of pre-treatment pharmacogenetic testing for predicting cancer prognosis and treatment exposure, response and toxicity”….

Price: ₹457.84
(as of Aug 08, 2023 06:17:09 UTC – Details)

Cancer treatment is complicated because of a multitude of treatment options and little patient-specific information to help clinicians choose appropriate therapy.
There are two genomes relevant in cancer treatment: the tumor (somatic) and the patient (germline).
Together, these two genomes dictate treatment outcome through four processes: the somatic genome primarily determines tumor prognosis and response while the germline genome modulates treatment exposure and toxicity.
In this booklet, the influence of these genomes on treatment outcomes by highlighting examples of genetic variation that are predictors of each of these four factors, prognosis, response, toxicity and exposure are being described, and discussed the translation and clinical implementation of each.
An attempt has been made to include several topics e.g. Brief History of Pharmacogenetics, Ethical issues, Limitation of Pharmacogenetic etc.
Use of pre-treatment pharmacogenetic testing will someday enable clinicians to make individualized therapy decisions about aggressiveness, drug selection and dose, improving treatment outcomes for cancer patients.
……..Dr.H.K.Saboowala.

ASIN ‏ : ‎ B0714H9Y81
Language ‏ : ‎ English
File size ‏ : ‎ 13576 KB
Text-to-Speech ‏ : ‎ Enabled
Screen Reader ‏ : ‎ Supported
Enhanced typesetting ‏ : ‎ Enabled
X-Ray ‏ : ‎ Not Enabled
Word Wise ‏ : ‎ Not Enabled
Print length ‏ : ‎ 61 pages